What are Famotidine and Omeprazole used for?

Both treat acid reflux/GERD and heartburn. Famotidine is an H2 blocker; Omeprazole is a proton pump inhibitor (PPI)

Famotidine reduces acid by blocking H2 receptors. Omeprazole shuts down proton pumps, lowering acid more strongly and for longer

Famotidine often gives relief within 1 hour. Omeprazole may take hours to days for full effect

Which is more effective for frequent symptoms/GERD?

For frequent or severe reflux, Omeprazole (PPI) usually provides stronger, longer control. For occasional heartburn, Famotidine is often enough

How long do effects last?

Famotidine: about 10–12 hours per dose. Omeprazole: 24-hour acid suppression with daily use

What are common side effects?

Famotidine: headache, dizziness, constipation/diarrhea (usually mild). Omeprazole: headache, nausea, gas, and with long use, potential low magnesium/B12 or bone concerns

Which is safer long-term?

Use the lowest effective dose. For short-term frequent reflux, PPIs are effective; reassess long-term need with a clinician. Consider lifestyle changes (weight, meals, triggers) and step-down to H2 blockers if possible

Category: Famotidine vs Omeprazole

Analyzing Efficacy and Safety: Famotidine vs Omeprazole in Acid Reflux Management

July 17, 2025

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Millions of people throughout the world have gastro-oesophageal reflux disease (GERD), which causes heartburn, regurgitation,...

Category: Famotidine vs Omeprazole

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